I’ve tried it once. I enjoyed it for the medical role play side, but the sensation of the sound itself didn’t do all that much for me. It wasn’t uncomfortable but just felt… kinda wrong.
Having said that I do want to give it a go again in future. I felt the same way about anal toys when I first tried them. Kinda wrong and uncomfortable, but that was just because it was new and I was awkward. So I want to give sounds another go because I might end up loving them. Medical play is a big fetish of mine.